5hnl

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(New page: '''Unreleased structure''' The entry 5hnl is ON HOLD Authors: Tsukui, S., Kimura, F., Kusaka, K., Baba, S., Mizuno, N., Kimura, T. Description: In-house X-ray single crystal diffractio...)
Current revision (10:48, 16 August 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5hnl is ON HOLD
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==In-house X-ray single crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels==
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<StructureSection load='5hnl' size='340' side='right'caption='[[5hnl]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5hnl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HNL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.424&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hnl OCA], [https://pdbe.org/5hnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hnl RCSB], [https://www.ebi.ac.uk/pdbsum/5hnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hnl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Protein microcrystals magnetically aligned in D2O hydrogels were subjected to neutron diffraction measurements, and reflections were observed for the first time to a resolution of 3.4 A from lysozyme microcrystals ( approximately 10 x 10 x 50 microm). This result demonstrated the possibility that magnetically oriented microcrystals consolidated in D2O gels may provide a promising means to obtain single-crystal neutron diffraction from proteins that do not crystallize at the sizes required for neutron diffraction structure determination. In addition, lysozyme microcrystals aligned in H2O hydrogels allowed structure determination at a resolution of 1.76 A at room temperature by X-ray diffraction. The use of gels has advantages since the microcrystals are measured under hydrated conditions.
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Authors: Tsukui, S., Kimura, F., Kusaka, K., Baba, S., Mizuno, N., Kimura, T.
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Neutron and X-ray single-crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels.,Tsukui S, Kimura F, Kusaka K, Baba S, Mizuno N, Kimura T Acta Crystallogr D Struct Biol. 2016 Jul 1;72(Pt 7):823-9. doi:, 10.1107/S2059798316007415. Epub 2016 Jun 23. PMID:27377379<ref>PMID:27377379</ref>
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Description: In-house X-ray single crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Kimura, T]]
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<div class="pdbe-citations 5hnl" style="background-color:#fffaf0;"></div>
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[[Category: Kimura, F]]
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[[Category: Mizuno, N]]
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==See Also==
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[[Category: Tsukui, S]]
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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[[Category: Baba, S]]
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== References ==
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[[Category: Kusaka, K]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Gallus gallus]]
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[[Category: Large Structures]]
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[[Category: Baba S]]
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[[Category: Kimura F]]
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[[Category: Kimura T]]
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[[Category: Kusaka K]]
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[[Category: Mizuno N]]
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[[Category: Tsukui S]]

Current revision

In-house X-ray single crystal diffraction from protein microcrystals via magnetically oriented microcrystal arrays in gels

PDB ID 5hnl

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