5huz
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase== | |
+ | <StructureSection load='5huz' size='340' side='right'caption='[[5huz]]' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[5huz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2mxr 2mxr]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HUZ FirstGlance]. <br> | ||
+ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5huz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5huz OCA], [https://pdbe.org/5huz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5huz RCSB], [https://www.ebi.ac.uk/pdbsum/5huz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5huz ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref> | ||
- | + | ==See Also== | |
- | + | *[[Protein phosphatase 3D structures|Protein phosphatase 3D structures]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Alper SL]] | ||
+ | [[Category: Anklin C]] | ||
+ | [[Category: Birrane G]] | ||
+ | [[Category: Pollak M]] | ||
+ | [[Category: Rigby AC]] | ||
+ | [[Category: Sharma AK]] |
Current revision
Solution structure of coiled coil domain of myosin binding subunit of myosin light chain phosphatase
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Categories: Homo sapiens | Large Structures | Alper SL | Anklin C | Birrane G | Pollak M | Rigby AC | Sharma AK