This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1pzm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:53, 16 August 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of HGPRT-ase from Leishmania tarentolae in complex with GMP==
==Crystal structure of HGPRT-ase from Leishmania tarentolae in complex with GMP==
-
<StructureSection load='1pzm' size='340' side='right' caption='[[1pzm]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
<StructureSection load='1pzm' size='340' side='right'caption='[[1pzm]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1pzm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leita Leita]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PZM FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1pzm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_tarentolae Leishmania tarentolae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PZM FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hgprt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5689 LEITA])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pzm OCA], [https://pdbe.org/1pzm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pzm RCSB], [https://www.ebi.ac.uk/pdbsum/1pzm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pzm ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pzm OCA], [http://pdbe.org/1pzm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1pzm RCSB], [http://www.ebi.ac.uk/pdbsum/1pzm PDBsum]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q9NJI5_LEITA Q9NJI5_LEITA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/1pzm_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/1pzm_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 29: Line 31:
==See Also==
==See Also==
-
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
+
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Hypoxanthine phosphoribosyltransferase]]
+
[[Category: Large Structures]]
-
[[Category: Leita]]
+
[[Category: Leishmania tarentolae]]
-
[[Category: Monzani, P S]]
+
[[Category: Monzani PS]]
-
[[Category: Oliva, G]]
+
[[Category: Oliva G]]
-
[[Category: Thiemann, O H]]
+
[[Category: Thiemann OH]]
-
[[Category: Trapani, S]]
+
[[Category: Trapani S]]
-
[[Category: Transferase]]
+

Current revision

Crystal structure of HGPRT-ase from Leishmania tarentolae in complex with GMP

PDB ID 1pzm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools