2iu6

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==REGULATION OF THE DHA OPERON OF LACTOCOCCUS LACTIS==
==REGULATION OF THE DHA OPERON OF LACTOCOCCUS LACTIS==
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<StructureSection load='2iu6' size='340' side='right' caption='[[2iu6]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2iu6' size='340' side='right'caption='[[2iu6]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2iu6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_lactis"_lister_1873 "bacterium lactis" lister 1873]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IU6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IU6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2iu6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IU6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IU6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iu4|2iu4]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu6 OCA], [https://pdbe.org/2iu6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iu6 RCSB], [https://www.ebi.ac.uk/pdbsum/2iu6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iu6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu6 OCA], [http://pdbe.org/2iu6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iu6 RCSB], [http://www.ebi.ac.uk/pdbsum/2iu6 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DHAQ_LACLA DHAQ_LACLA] Coactivator for the transcription factor DhaS. The heterotetramer formed by DhaQ and DhaS functions as transcriptional regulator. Activated by covalent binding of dihydroxyacetone to DhaQ. The complex activates the dhaKLM operon.<ref>PMID:16760471</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/2iu6_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/2iu6_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacterium lactis lister 1873]]
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[[Category: Lactococcus lactis]]
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[[Category: Glucokinase]]
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[[Category: Large Structures]]
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[[Category: Baumann, U]]
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[[Category: Baumann U]]
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[[Category: Christen, S]]
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[[Category: Christen S]]
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[[Category: Erni, B]]
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[[Category: Erni B]]
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[[Category: Srinivas, A]]
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[[Category: Srinivas A]]
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[[Category: Dihydroxyacetone kinase transferase]]
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[[Category: Kinase]]
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[[Category: Transferase]]
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Current revision

REGULATION OF THE DHA OPERON OF LACTOCOCCUS LACTIS

PDB ID 2iu6

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