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3ez3
From Proteopedia
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==Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound== | ==Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound== | ||
| - | <StructureSection load='3ez3' size='340' side='right' caption='[[3ez3]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='3ez3' size='340' side='right'caption='[[3ez3]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ez3]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ez3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EZ3 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.304Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPE:3-METHYLBUT-3-ENYL+TRIHYDROGEN+DIPHOSPHATE'>IPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZOL:ZOLEDRONIC+ACID'>ZOL</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ez3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ez3 OCA], [https://pdbe.org/3ez3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ez3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ez3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ez3 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A5K4U6_PLAVS A5K4U6_PLAVS] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ez/3ez3_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ez/3ez3_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
| - | *[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]] | + | *[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Plasmodium vivax]] |
| - | [[Category: Artz | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bochkarev | + | [[Category: Artz JD]] |
| - | [[Category: Bountra | + | [[Category: Bochkarev A]] |
| - | [[Category: Cossar | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Cossar D]] |
| - | [[Category: Hui | + | [[Category: Edwards AM]] |
| - | [[Category: Kozieradzki | + | [[Category: Hui R]] |
| - | [[Category: Lew | + | [[Category: Kozieradzki I]] |
| - | + | [[Category: Lew J]] | |
| - | [[Category: Schapira | + | [[Category: Schapira M]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Wernimont | + | [[Category: Wernimont AK]] |
| - | [[Category: Zhao | + | [[Category: Zhao Y]] |
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Current revision
Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound
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Categories: Large Structures | Plasmodium vivax | Arrowsmith CH | Artz JD | Bochkarev A | Bountra C | Cossar D | Edwards AM | Hui R | Kozieradzki I | Lew J | Schapira M | Weigelt J | Wernimont AK | Zhao Y
