3ado

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==Crystal Structure of the Rabbit L-Gulonate 3-Dehydrogenase==
==Crystal Structure of the Rabbit L-Gulonate 3-Dehydrogenase==
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<StructureSection load='3ado' size='340' side='right' caption='[[3ado]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='3ado' size='340' side='right'caption='[[3ado]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ado]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2dpo 2dpo]. The July 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Crystallins'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_7 10.2210/rcsb_pdb/mom_2010_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ADO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ADO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ado]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2dpo 2dpo]. The July 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Crystallins'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_7 10.2210/rcsb_pdb/mom_2010_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ADO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ADO FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3adp|3adp]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRYL1, GUL3DH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9986 European rabbit])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ado FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ado OCA], [https://pdbe.org/3ado PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ado RCSB], [https://www.ebi.ac.uk/pdbsum/3ado PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ado ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-gulonate_3-dehydrogenase L-gulonate 3-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.45 1.1.1.45] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ado FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ado OCA], [http://pdbe.org/3ado PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ado RCSB], [http://www.ebi.ac.uk/pdbsum/3ado PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CRYL1_RABIT CRYL1_RABIT]] Functions as crystallin in the rabbit eye lens. Has high L-gulonate 3-dehydrogenase activity.
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[https://www.uniprot.org/uniprot/CRYL1_RABIT CRYL1_RABIT] Functions as crystallin in the rabbit eye lens. Has high L-gulonate 3-dehydrogenase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/3ado_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/3ado_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</StructureSection>
</StructureSection>
[[Category: Crystallins]]
[[Category: Crystallins]]
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[[Category: European rabbit]]
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[[Category: Large Structures]]
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[[Category: L-gulonate 3-dehydrogenase]]
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[[Category: Oryctolagus cuniculus]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Asada, Y]]
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[[Category: Asada Y]]
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[[Category: Hara, A]]
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[[Category: Hara A]]
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[[Category: Kunishima, N]]
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[[Category: Kunishima N]]
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[[Category: Structural genomic]]
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[[Category: Eye lens protein]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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[[Category: Rsgi]]
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Current revision

Crystal Structure of the Rabbit L-Gulonate 3-Dehydrogenase

PDB ID 3ado

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