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3dez

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==Crystal structure of Orotate phosphoribosyltransferase from Streptococcus mutans==
==Crystal structure of Orotate phosphoribosyltransferase from Streptococcus mutans==
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<StructureSection load='3dez' size='340' side='right' caption='[[3dez]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='3dez' size='340' side='right'caption='[[3dez]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3dez]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25175 Atcc 25175]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DEZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3dez]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DEZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dez OCA], [https://pdbe.org/3dez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dez RCSB], [https://www.ebi.ac.uk/pdbsum/3dez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dez ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dez OCA], [http://pdbe.org/3dez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dez RCSB], [http://www.ebi.ac.uk/pdbsum/3dez PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PYRE_STRMU PYRE_STRMU]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
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[https://www.uniprot.org/uniprot/PYRE_STRMU PYRE_STRMU] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/3dez_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/3dez_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 25175]]
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[[Category: Large Structures]]
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[[Category: Orotate phosphoribosyltransferase]]
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[[Category: Streptococcus mutans]]
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[[Category: Dong, Y H]]
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[[Category: Dong YH]]
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[[Category: Gao, Z Q]]
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[[Category: Gao ZQ]]
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[[Category: Hou, H F]]
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[[Category: Hou HF]]
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[[Category: Li, L F]]
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[[Category: Li LF]]
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[[Category: Liu, C P]]
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[[Category: Liu CP]]
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[[Category: Su, X D]]
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[[Category: Su XD]]
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[[Category: Glycosyltransferase]]
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[[Category: Magnesium]]
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[[Category: Pyrimidine biosynthesis]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Orotate phosphoribosyltransferase from Streptococcus mutans

PDB ID 3dez

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