2nap

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==DISSIMILATORY NITRATE REDUCTASE (NAP) FROM DESULFOVIBRIO DESULFURICANS==
==DISSIMILATORY NITRATE REDUCTASE (NAP) FROM DESULFOVIBRIO DESULFURICANS==
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<StructureSection load='2nap' size='340' side='right' caption='[[2nap]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='2nap' size='340' side='right'caption='[[2nap]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NAP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nap]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NAP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MO:MOLYBDENUM+ATOM'>MO</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nap OCA], [http://pdbe.org/2nap PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nap RCSB], [http://www.ebi.ac.uk/pdbsum/2nap PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MO:MOLYBDENUM+ATOM'>MO</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nap OCA], [https://pdbe.org/2nap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nap RCSB], [https://www.ebi.ac.uk/pdbsum/2nap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nap ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NAPA_DESDA NAPA_DESDA] Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/2nap_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/2nap_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</StructureSection>
</StructureSection>
[[Category: Desulfovibrio desulfuricans]]
[[Category: Desulfovibrio desulfuricans]]
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[[Category: Bartunik, H]]
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[[Category: Large Structures]]
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[[Category: Bourenkov, G]]
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[[Category: Bartunik H]]
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[[Category: Bursakov, S]]
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[[Category: Bourenkov G]]
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[[Category: Caldeira, J]]
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[[Category: Bursakov S]]
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[[Category: Calvete, J]]
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[[Category: Caldeira J]]
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[[Category: Carneiro, C]]
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[[Category: Calvete J]]
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[[Category: Dias, J M]]
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[[Category: Carneiro C]]
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[[Category: Huber, R]]
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[[Category: Dias JM]]
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[[Category: Humm, A]]
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[[Category: Huber R]]
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[[Category: Moura, I]]
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[[Category: Humm A]]
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[[Category: Moura, J]]
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[[Category: Moura I]]
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[[Category: Romao, M J]]
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[[Category: Moura J]]
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[[Category: Than, M]]
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[[Category: Romao MJ]]
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[[Category: Dissimilatory nitrate reductase]]
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[[Category: Than M]]
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[[Category: Molybdopterin cofactor]]
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[[Category: Multiwavelength anomalous diffraction]]
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[[Category: Nitrogenous acceptor]]
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[[Category: Oxidoreductase]]
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Current revision

DISSIMILATORY NITRATE REDUCTASE (NAP) FROM DESULFOVIBRIO DESULFURICANS

PDB ID 2nap

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