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2yvv

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==Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites==
==Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites==
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<StructureSection load='2yvv' size='340' side='right' caption='[[2yvv]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='2yvv' size='340' side='right'caption='[[2yvv]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yvv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YVV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yvv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YVV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBT:ALPHA-LACTOSE'>LBT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dp5|2dp5]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900008:alpha-lactose'>PRD_900008</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HYL P2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1314 "Micrococcus scarlatinae" Klein 1884])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yvv OCA], [https://pdbe.org/2yvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yvv RCSB], [https://www.ebi.ac.uk/pdbsum/2yvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yvv ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hyaluronate_lyase Hyaluronate lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.2.1 4.2.2.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yvv OCA], [http://pdbe.org/2yvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yvv RCSB], [http://www.ebi.ac.uk/pdbsum/2yvv PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9A0M7_STRP1 Q9A0M7_STRP1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/2yvv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/2yvv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Hyaluronidase|Hyaluronidase]]
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*[[Hyaluronidase 3D structures|Hyaluronidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Micrococcus scarlatinae klein 1884]]
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[[Category: Large Structures]]
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[[Category: Hyaluronate lyase]]
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[[Category: Streptococcus pyogenes]]
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[[Category: Betzel, C]]
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[[Category: Betzel C]]
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[[Category: Bhakuni, V]]
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[[Category: Bhakuni V]]
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[[Category: Kaur, P]]
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[[Category: Kaur P]]
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[[Category: Kumar, R Prem]]
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[[Category: Mishra P]]
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[[Category: Mishra, P]]
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[[Category: Perbandt M]]
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[[Category: Perbandt, M]]
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[[Category: Prem Kumar R]]
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[[Category: Sharma, S]]
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[[Category: Sharma S]]
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[[Category: Singh, N]]
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[[Category: Singh N]]
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[[Category: Singh, T P]]
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[[Category: Singh TP]]
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[[Category: Complex]]
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[[Category: Hyaluronan lyase]]
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[[Category: Hyaluronidase]]
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[[Category: Lactose]]
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[[Category: Lyase]]
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Current revision

Crystal structure of hyluranidase complexed with lactose at 2.6 A resolution reveals three specific sugar recognition sites

PDB ID 2yvv

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