This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2zcr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:31, 1 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-698==
==Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-698==
-
<StructureSection load='2zcr' size='340' side='right' caption='[[2zcr]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
+
<StructureSection load='2zcr' size='340' side='right'caption='[[2zcr]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2zcr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZCR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZCR FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2zcr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZCR FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B69:TRIPOTASSIUM+(1R)-4-(4-BUTYLBIPHENYL-4-YL)-1-PHOSPHONATOBUTANE-1-SULFONATE'>B69</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zco|2zco]], [[2zcp|2zcp]], [[2zcq|2zcq]], [[2zcs|2zcs]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B69:TRIPOTASSIUM+(1R)-4-(4-BUTYLBIPHENYL-4-YL)-1-PHOSPHONATOBUTANE-1-SULFONATE'>B69</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CrtM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zcr OCA], [https://pdbe.org/2zcr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zcr RCSB], [https://www.ebi.ac.uk/pdbsum/2zcr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zcr ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zcr OCA], [http://pdbe.org/2zcr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zcr RCSB], [http://www.ebi.ac.uk/pdbsum/2zcr PDBsum]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CRTM_STAAU CRTM_STAAU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zc/2zcr_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zc/2zcr_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 27: Line 29:
</div>
</div>
<div class="pdbe-citations 2zcr" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2zcr" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Squalene synthase|Squalene synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Jeng, W Y]]
+
[[Category: Large Structures]]
-
[[Category: Liu, C I]]
+
[[Category: Staphylococcus aureus]]
-
[[Category: Oldfield, E]]
+
[[Category: Jeng WY]]
-
[[Category: Wang, A H]]
+
[[Category: Liu CI]]
-
[[Category: Bisphosphonate]]
+
[[Category: Oldfield E]]
-
[[Category: Carotenoid biosynthesis]]
+
[[Category: Wang AH]]
-
[[Category: Crtm]]
+
-
[[Category: Head-to-head condensation]]
+
-
[[Category: Staphyloxanthin biosynthesis]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-698

PDB ID 2zcr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2zcr"
Personal tools