2nmm

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==Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409==
==Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409==
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<StructureSection load='2nmm' size='340' side='right' caption='[[2nmm]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='2nmm' size='340' side='right'caption='[[2nmm]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nmm]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NMM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NMM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nmm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NMM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NMM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHPT1, PHP14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nmm OCA], [https://pdbe.org/2nmm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nmm RCSB], [https://www.ebi.ac.uk/pdbsum/2nmm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nmm ProSAT], [https://www.topsan.org/Proteins/NESGC/2nmm TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nmm OCA], [http://pdbe.org/2nmm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nmm RCSB], [http://www.ebi.ac.uk/pdbsum/2nmm PDBsum], [http://www.topsan.org/Proteins/NESGC/2nmm TOPSAN]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PHP14_HUMAN PHP14_HUMAN]] Exhibits phosphohistidine phosphatase activity.
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[https://www.uniprot.org/uniprot/PHP14_HUMAN PHP14_HUMAN] Exhibits phosphohistidine phosphatase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/2nmm_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/2nmm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Abashidze, M]]
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[[Category: Large Structures]]
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[[Category: Acton, T]]
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[[Category: Abashidze M]]
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[[Category: Conover, K]]
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[[Category: Acton T]]
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[[Category: Cunningham, K]]
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[[Category: Conover K]]
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[[Category: Fang, Y]]
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[[Category: Cunningham K]]
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[[Category: Forouhar, F]]
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[[Category: Fang Y]]
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[[Category: Hunt, J F]]
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[[Category: Forouhar F]]
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[[Category: Kent, C]]
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[[Category: Hunt JF]]
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[[Category: Kuzin, A P]]
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[[Category: Kent C]]
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[[Category: Ma, L C]]
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[[Category: Kuzin AP]]
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[[Category: Montelione, G]]
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[[Category: Ma LC]]
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[[Category: Structural genomic]]
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[[Category: Montelione G]]
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[[Category: Seetharaman, J]]
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[[Category: Seetharaman J]]
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[[Category: Tong, L]]
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[[Category: Tong L]]
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[[Category: Xiao, R]]
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[[Category: Xiao R]]
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[[Category: Hydrolase]]
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[[Category: Nesg q9h0y3 human phosphohistidine phosphatase]]
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[[Category: PSI, Protein structure initiative]]
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Current revision

Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409

PDB ID 2nmm

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