2wlv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:14, 9 May 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Structure of the N-terminal capsid domain of HIV-2==
==Structure of the N-terminal capsid domain of HIV-2==
-
<StructureSection load='2wlv' size='340' side='right' caption='[[2wlv]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
+
<StructureSection load='2wlv' size='340' side='right'caption='[[2wlv]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2wlv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-2 Hiv-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLV FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2wlv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_2_(ISOLATE_D194) Human immunodeficiency virus type 2 (ISOLATE D194)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLV FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wlw|2wlw]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlv OCA], [http://pdbe.org/2wlv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wlv RCSB], [http://www.ebi.ac.uk/pdbsum/2wlv PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wlv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlv OCA], [https://pdbe.org/2wlv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wlv RCSB], [https://www.ebi.ac.uk/pdbsum/2wlv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/Q76929_9HIV2 Q76929_9HIV2]] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).[SAAS:SAAS012344_004_008806] Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).
+
[https://www.uniprot.org/uniprot/GAG_HV2RO GAG_HV2RO] Matrix protein p17 targets Gag and Gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal. Also mediates nuclear localization of the preintegration complex (By similarity). Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity). p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wlv_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wlv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 30: Line 31:
==See Also==
==See Also==
*[[Gag polyprotein|Gag polyprotein]]
*[[Gag polyprotein|Gag polyprotein]]
 +
*[[Gag polyprotein 3D structures|Gag polyprotein 3D structures]]
 +
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Hiv-2]]
+
[[Category: Large Structures]]
-
[[Category: James, L C]]
+
[[Category: James LC]]
-
[[Category: Lammers, M]]
+
[[Category: Lammers M]]
-
[[Category: Marzetta, F]]
+
[[Category: Marzetta F]]
-
[[Category: Price, A J]]
+
[[Category: Price AJ]]
-
[[Category: Schaller, T]]
+
[[Category: Schaller T]]
-
[[Category: Towers, G J]]
+
[[Category: Towers GJ]]
-
[[Category: Wilson, S J]]
+
[[Category: Wilson SJ]]
-
[[Category: Ylinen, L M.J]]
+
[[Category: Ylinen LMJ]]
-
[[Category: Aid]]
+
-
[[Category: Capsid protein]]
+
-
[[Category: Hiv]]
+
-
[[Category: Hiv-1]]
+
-
[[Category: Rna-binding]]
+
-
[[Category: Viral nucleoprotein]]
+
-
[[Category: Viral protein]]
+

Current revision

Structure of the N-terminal capsid domain of HIV-2

PDB ID 2wlv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2wlv"
Personal tools