2ap9

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==Crystal structure of acetylglutamate kinase from Mycobacterium tuberculosis CDC1551==
==Crystal structure of acetylglutamate kinase from Mycobacterium tuberculosis CDC1551==
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<StructureSection load='2ap9' size='340' side='right' caption='[[2ap9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='2ap9' size='340' side='right'caption='[[2ap9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ap9]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycto Mycto]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AP9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AP9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ap9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_CDC1551 Mycobacterium tuberculosis CDC1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AP9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AP9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">argB, Rv1654, MT1692 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83331 MYCTO])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ap9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ap9 OCA], [https://pdbe.org/2ap9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ap9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ap9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ap9 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ap9 TOPSAN]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ap9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ap9 OCA], [http://pdbe.org/2ap9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ap9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ap9 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2ap9 TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARGB_MYCTU ARGB_MYCTU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ap/2ap9_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ap/2ap9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acetylglutamate kinase]]
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[[Category: Large Structures]]
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[[Category: Mycto]]
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[[Category: Mycobacterium tuberculosis CDC1551]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Kniewel, R]]
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[[Category: Kniewel R]]
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[[Category: Lee, K]]
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[[Category: Lee K]]
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[[Category: Lima, C D]]
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[[Category: Lima CD]]
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[[Category: Structural genomic]]
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[[Category: Rajashankar KR]]
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[[Category: Rajashankar, K R]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Signaling protein]]
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[[Category: T1702]]
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[[Category: Transferase]]
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Current revision

Crystal structure of acetylglutamate kinase from Mycobacterium tuberculosis CDC1551

PDB ID 2ap9

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