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2qpf

From Proteopedia

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==Crystal Structure of Mouse Transthyretin==
==Crystal Structure of Mouse Transthyretin==
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<StructureSection load='2qpf' size='340' side='right' caption='[[2qpf]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='2qpf' size='340' side='right'caption='[[2qpf]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qpf]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QPF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qpf]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QPF FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ttr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qpf OCA], [http://pdbe.org/2qpf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qpf RCSB], [http://www.ebi.ac.uk/pdbsum/2qpf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qpf OCA], [https://pdbe.org/2qpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qpf RCSB], [https://www.ebi.ac.uk/pdbsum/2qpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qpf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TTHY_MOUSE TTHY_MOUSE]] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
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[https://www.uniprot.org/uniprot/TTHY_MOUSE TTHY_MOUSE] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qp/2qpf_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qp/2qpf_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Transthyretin|Transthyretin]]
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*[[Transthyretin 3D structures|Transthyretin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Buxbaum, J N]]
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[[Category: Mus musculus]]
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[[Category: Foss, T R]]
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[[Category: Buxbaum JN]]
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[[Category: Kelly, J W]]
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[[Category: Foss TR]]
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[[Category: Pascual, J]]
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[[Category: Kelly JW]]
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[[Category: Reixach, N]]
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[[Category: Pascual J]]
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[[Category: Santelli, E]]
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[[Category: Reixach N]]
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[[Category: Amyloidogenesis]]
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[[Category: Santelli E]]
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[[Category: Glycoprotein]]
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[[Category: Hormone]]
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[[Category: Retinol-binding]]
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[[Category: Secreted]]
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[[Category: Tetramer]]
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[[Category: Thyroid hormone]]
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[[Category: Transport protein]]
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[[Category: Vitamin some]]
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Current revision

Crystal Structure of Mouse Transthyretin

PDB ID 2qpf

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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