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2kmq
From Proteopedia
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==Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.== | ==Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.== | ||
| - | <StructureSection load='2kmq' size='340' side='right' caption='[[2kmq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2kmq' size='340' side='right'caption='[[2kmq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kmq]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kmq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hirme Hirme]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KMQ FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2kmo|2kmo]], [[2kmp|2kmp]], [[2kmr|2kmr]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2kmo|2kmo]], [[2kmp|2kmp]], [[2kmr|2kmr]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kmq OCA], [https://pdbe.org/2kmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kmq RCSB], [https://www.ebi.ac.uk/pdbsum/2kmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kmq ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/LDTI_HIRME LDTI_HIRME]] Acts as an inhibitor of human tryptase, trypsin and chymotrypsin. Probably acts to block host defense mechanisms. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/km/2kmq_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/km/2kmq_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Hirme]] | [[Category: Hirme]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Pantoja-Uceda, D]] | [[Category: Pantoja-Uceda, D]] | ||
[[Category: Santoro, J]] | [[Category: Santoro, J]] | ||
Current revision
Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.
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