2qzf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:28, 6 November 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==SCR1 of DAF from 1ojv fitted into cryoEM density==
==SCR1 of DAF from 1ojv fitted into cryoEM density==
-
<StructureSection load='2qzf' size='340' side='right' caption='[[2qzf]], [[Resolution|resolution]] 14.00&Aring;' scene=''>
+
<SX load='2qzf' size='340' side='right' viewer='molstar' caption='[[2qzf]], [[Resolution|resolution]] 14.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2qzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QZF FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2qzf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QZF FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qzf OCA], [http://pdbe.org/2qzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qzf RCSB], [http://www.ebi.ac.uk/pdbsum/2qzf PDBsum]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qzf OCA], [https://pdbe.org/2qzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qzf RCSB], [https://www.ebi.ac.uk/pdbsum/2qzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qzf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
+
[https://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/2qzf_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qz/2qzf_consurf.spt"</scriptWhenChecked>
-
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
Line 26: Line 28:
</div>
</div>
<div class="pdbe-citations 2qzf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2qzf" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[CD55|CD55]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
-
</StructureSection>
+
</SX>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Bowman, V D]]
+
[[Category: Large Structures]]
-
[[Category: Chipman, P R]]
+
[[Category: Bator Kelly CM]]
-
[[Category: Hafenstein, S]]
+
[[Category: Bowman VD]]
-
[[Category: Kelly, C M.Bator]]
+
[[Category: Chipman PR]]
-
[[Category: Lin, F]]
+
[[Category: Hafenstein S]]
-
[[Category: Medof, M E]]
+
[[Category: Lin F]]
-
[[Category: Rossmann, M G]]
+
[[Category: Medof ME]]
-
[[Category: Blood group antigen]]
+
[[Category: Rossmann MG]]
-
[[Category: Complement pathway]]
+
-
[[Category: Glycoprotein]]
+
-
[[Category: Gpi-anchor]]
+
-
[[Category: Immune response]]
+
-
[[Category: Immune system]]
+
-
[[Category: Innate immunity]]
+
-
[[Category: Lipoprotein]]
+
-
[[Category: Membrane]]
+
-
[[Category: Scr1 of daf from structure 1ojv fitted into cryoem density]]
+
-
[[Category: Sushi]]
+

Current revision

SCR1 of DAF from 1ojv fitted into cryoEM density

2qzf, resolution 14.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2qzf"
Personal tools