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3fm3
From Proteopedia
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==Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2== | ==Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2== | ||
| - | <StructureSection load='3fm3' size='340' side='right' caption='[[3fm3]], [[Resolution|resolution]] 2.18Å' scene=''> | + | <StructureSection load='3fm3' size='340' side='right'caption='[[3fm3]], [[Resolution|resolution]] 2.18Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3fm3]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3fm3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Encephalitozoon_cuniculi Encephalitozoon cuniculi]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2nw5 2nw5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FM3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fm3 OCA], [https://pdbe.org/3fm3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fm3 RCSB], [https://www.ebi.ac.uk/pdbsum/3fm3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fm3 ProSAT]</span></td></tr> |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MAP2_ENCCU MAP2_ENCCU] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).[HAMAP-Rule:MF_03175]<ref>PMID:14736176</ref> <ref>PMID:16004378</ref> <ref>PMID:16917013</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/3fm3_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/3fm3_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
| - | *[[Aminopeptidase|Aminopeptidase]] | + | *[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Enccn]] | ||
| - | [[Category: Methionyl aminopeptidase]] | ||
| - | [[Category: Adams, J]] | ||
| - | [[Category: Almo, S C]] | ||
| - | [[Category: Alvarado, J J]] | ||
| - | [[Category: Burley, S K]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Russell, M]] | ||
| - | [[Category: Toro, R]] | ||
| - | [[Category: Weiss, L M]] | ||
| - | [[Category: Zhang, A]] | ||
| - | [[Category: Aminopeptidase]] | ||
| - | [[Category: Cobalt]] | ||
[[Category: Encephalitozoon cuniculi]] | [[Category: Encephalitozoon cuniculi]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Adams J]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Alvarado JJ]] |
| - | [[Category: | + | [[Category: Burley SK]] |
| - | [[Category: | + | [[Category: Russell M]] |
| - | [[Category: | + | [[Category: Toro R]] |
| + | [[Category: Weiss LM]] | ||
| + | [[Category: Zhang A]] | ||
Current revision
Crystal structure of an Encephalitozoon cuniculi methionine aminopeptidase type 2
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Categories: Encephalitozoon cuniculi | Large Structures | Adams J | Almo SC | Alvarado JJ | Burley SK | Russell M | Toro R | Weiss LM | Zhang A
