2w2s
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2w2s' size='340' side='right' caption='[[2w2s]], [[Resolution|resolution]] 2.75Å' scene=''> | + | ==Structure of the Lagos bat virus matrix protein== |
| + | <StructureSection load='2w2s' size='340' side='right'caption='[[2w2s]], [[Resolution|resolution]] 2.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2w2s]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2w2s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lagos_bat_lyssavirus Lagos bat lyssavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W2S FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w2s OCA], [https://pdbe.org/2w2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w2s RCSB], [https://www.ebi.ac.uk/pdbsum/2w2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w2s ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MATRX_LBV MATRX_LBV] Plays a major role in assembly and budding of virion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/2w2s_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/2w2s_consurf.spt"</scriptWhenChecked> |
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Lagos bat lyssavirus]] |
| - | [[Category: Assenberg | + | [[Category: Large Structures]] |
| - | [[Category: Bourhy | + | [[Category: Assenberg R]] |
| - | [[Category: Delmas | + | [[Category: Bourhy H]] |
| - | [[Category: Gholami | + | [[Category: Delmas O]] |
| - | [[Category: Graham | + | [[Category: Gholami A]] |
| - | [[Category: Grimes | + | [[Category: Graham SC]] |
| - | [[Category: Owens | + | [[Category: Grimes JM]] |
| - | [[Category: Stuart | + | [[Category: Owens RJ]] |
| - | [[Category: Talbi | + | [[Category: Stuart DI]] |
| - | [[Category: Verma | + | [[Category: Talbi C]] |
| - | + | [[Category: Verma A]] | |
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Current revision
Structure of the Lagos bat virus matrix protein
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Categories: Lagos bat lyssavirus | Large Structures | Assenberg R | Bourhy H | Delmas O | Gholami A | Graham SC | Grimes JM | Owens RJ | Stuart DI | Talbi C | Verma A

