3da2
From Proteopedia
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==X-ray structure of human carbonic anhydrase 13 in complex with inhibitor== | ==X-ray structure of human carbonic anhydrase 13 in complex with inhibitor== | ||
| - | <StructureSection load='3da2' size='340' side='right' caption='[[3da2]], [[Resolution|resolution]] 2.05Å' scene=''> | + | <StructureSection load='3da2' size='340' side='right'caption='[[3da2]], [[Resolution|resolution]] 2.05Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3da2]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3da2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DA2 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4MD:N-(4-CHLOROBENZYL)-N-METHYLBENZENE-1,4-DISULFONAMIDE'>4MD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MD:N-(4-CHLOROBENZYL)-N-METHYLBENZENE-1,4-DISULFONAMIDE'>4MD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3da2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3da2 OCA], [https://pdbe.org/3da2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3da2 RCSB], [https://www.ebi.ac.uk/pdbsum/3da2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3da2 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CAH13_HUMAN CAH13_HUMAN] Reversible hydration of carbon dioxide. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/da/3da2_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/da/3da2_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
| - | *[[Carbonic anhydrase|Carbonic anhydrase]] | + | *[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Bray | + | [[Category: Bray JE]] |
| - | + | [[Category: Edwards AM]] | |
| - | [[Category: Edwards | + | [[Category: Filippakopoulos P]] |
| - | [[Category: Filippakopoulos | + | [[Category: King ONF]] |
| - | [[Category: King | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Picaud SS]] |
| - | [[Category: Picaud | + | [[Category: Pike ACW]] |
| - | [[Category: Pike | + | [[Category: Pilka ES]] |
| - | [[Category: Pilka | + | [[Category: Roos AK]] |
| - | [[Category: Roos | + | [[Category: Wikstrom M]] |
| - | + | [[Category: Yue WW]] | |
| - | [[Category: Wikstrom | + | [[Category: Von Delft F]] |
| - | [[Category: Yue | + | |
| - | [[Category: | + | |
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Current revision
X-ray structure of human carbonic anhydrase 13 in complex with inhibitor
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Bray JE | Edwards AM | Filippakopoulos P | King ONF | Oppermann U | Picaud SS | Pike ACW | Pilka ES | Roos AK | Wikstrom M | Yue WW | Von Delft F
