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3flv

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==The crystal structure of human acyl-CoenzymeA binding domain containing 5==
==The crystal structure of human acyl-CoenzymeA binding domain containing 5==
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<StructureSection load='3flv' size='340' side='right' caption='[[3flv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='3flv' size='340' side='right'caption='[[3flv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3flv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FLV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FLV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3flv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FLV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FLV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1hbk|1hbk]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ACBD5, KIAA1996 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3flv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3flv OCA], [https://pdbe.org/3flv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3flv RCSB], [https://www.ebi.ac.uk/pdbsum/3flv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3flv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3flv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3flv OCA], [http://pdbe.org/3flv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3flv RCSB], [http://www.ebi.ac.uk/pdbsum/3flv PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACBD5_HUMAN ACBD5_HUMAN]] Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.<ref>PMID:24535825</ref>
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[https://www.uniprot.org/uniprot/ACBD5_HUMAN ACBD5_HUMAN] Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.<ref>PMID:24535825</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/3flv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/3flv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Bountra, C]]
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[[Category: Arrowsmith CH]]
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[[Category: Delft, F von]]
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[[Category: Bountra C]]
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[[Category: Edwards, A]]
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[[Category: Edwards A]]
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[[Category: Muniz, J R.C]]
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[[Category: Muniz JRC]]
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[[Category: Oppermann, U]]
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[[Category: Oppermann U]]
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[[Category: Roos, A]]
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[[Category: Roos A]]
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[[Category: Structural genomic]]
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[[Category: Salah E]]
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[[Category: Salah, E]]
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[[Category: Savitsky P]]
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[[Category: Savitsky, P]]
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[[Category: Shafqat N]]
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[[Category: Shafqat, N]]
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[[Category: Ugochukwu E]]
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[[Category: Ugochukwu, E]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Yue WW]]
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[[Category: Yue, W W]]
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[[Category: Von Delft F]]
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[[Category: Acyl-coa binding]]
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[[Category: Lipid binding]]
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[[Category: Lipid binding protein]]
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[[Category: Lipid-binding]]
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[[Category: Membrane]]
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[[Category: Phosphoprotein]]
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[[Category: Sgc]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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Current revision

The crystal structure of human acyl-CoenzymeA binding domain containing 5

PDB ID 3flv

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