2eob
From Proteopedia
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==Solution structure of the second SH2 domain from rat PLC gamma-2==  | ==Solution structure of the second SH2 domain from rat PLC gamma-2==  | ||
| - | <StructureSection load='2eob' size='340' side='right' caption='[[2eob  | + | <StructureSection load='2eob' size='340' side='right'caption='[[2eob]]' scene=''>  | 
== Structural highlights ==  | == Structural highlights ==  | ||
| - | <table><tr><td colspan='2'>[[2eob]] is a 1 chain structure with sequence from [  | + | <table><tr><td colspan='2'>[[2eob]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EOB FirstGlance]. <br>  | 
| - | </td></tr><tr id='  | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>  | 
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eob OCA], [https://pdbe.org/2eob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eob RCSB], [https://www.ebi.ac.uk/pdbsum/2eob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eob ProSAT], [https://www.topsan.org/Proteins/RSGI/2eob TOPSAN]</span></td></tr>  | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[  | + | |
</table>  | </table>  | ||
== Function ==  | == Function ==  | ||
| - | [  | + | [https://www.uniprot.org/uniprot/PLCG2_RAT PLCG2_RAT] The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.  | 
== Evolutionary Conservation ==  | == Evolutionary Conservation ==  | ||
[[Image:Consurf_key_small.gif|200px|right]]  | [[Image:Consurf_key_small.gif|200px|right]]  | ||
Check<jmol>  | Check<jmol>  | ||
  <jmolCheckbox>  |   <jmolCheckbox>  | ||
| - |     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eob_consurf.spt"</scriptWhenChecked>  | + |     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eob_consurf.spt"</scriptWhenChecked>  | 
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>  |     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>  | ||
    <text>to colour the structure by Evolutionary Conservation</text>  |     <text>to colour the structure by Evolutionary Conservation</text>  | ||
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__TOC__  | __TOC__  | ||
</StructureSection>  | </StructureSection>  | ||
| - | [[Category:   | + | [[Category: Large Structures]]  | 
| - | [[Category:   | + | [[Category: Rattus norvegicus]]  | 
| - | [[Category: Hayashi  | + | [[Category: Hayashi F]]  | 
| - | [[Category: Nagashima  | + | [[Category: Nagashima T]]  | 
| - | + | [[Category: Sano R]]  | |
| - | [[Category: Sano  | + | [[Category: Yokoyama S]]  | 
| - | [[Category: Yokoyama  | + | [[Category: Yoshida M]]  | 
| - | [[Category: Yoshida  | + | |
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Current revision
Solution structure of the second SH2 domain from rat PLC gamma-2
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