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1r1t

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==Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form==
==Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form==
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<StructureSection load='1r1t' size='340' side='right' caption='[[1r1t]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='1r1t' size='340' side='right'caption='[[1r1t]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1r1t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Anacystis_nidulans_r2 Anacystis nidulans r2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R1T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1R1T FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1r1t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_elongatus_PCC_7942_=_FACHB-805 Synechococcus elongatus PCC 7942 = FACHB-805]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R1T FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1smt|1smt]], [[1riu|1riu]], [[1riv|1riv]], [[1r22|1r22]], [[1r23|1r23]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMTB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1140 Anacystis nidulans R2])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r1t OCA], [https://pdbe.org/1r1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r1t RCSB], [https://www.ebi.ac.uk/pdbsum/1r1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r1t ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r1t OCA], [http://pdbe.org/1r1t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1r1t RCSB], [http://www.ebi.ac.uk/pdbsum/1r1t PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SMTB_SYNE7 SMTB_SYNE7]] Transcriptional repressor of the expression of the smtA gene. Binds two zinc ions per dimer. The complex of DNA and SmtB is dissociated by zinc ions.<ref>PMID:12146943</ref> <ref>PMID:12407207</ref> <ref>PMID:8871549</ref>
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[https://www.uniprot.org/uniprot/SMTB_SYNE7 SMTB_SYNE7] Transcriptional repressor of the expression of the smtA gene. Binds two zinc ions per dimer. The complex of DNA and SmtB is dissociated by zinc ions.<ref>PMID:12146943</ref> <ref>PMID:12407207</ref> <ref>PMID:8871549</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/1r1t_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/1r1t_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anacystis nidulans r2]]
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[[Category: Large Structures]]
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[[Category: Chen, X]]
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[[Category: Synechococcus elongatus PCC 7942 = FACHB-805]]
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[[Category: Eicken, C]]
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[[Category: Chen X]]
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[[Category: Giedroc, D P]]
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[[Category: Eicken C]]
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[[Category: Koshlap, K M]]
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[[Category: Giedroc DP]]
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[[Category: Pennella, M A]]
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[[Category: Koshlap KM]]
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[[Category: Sacchettini, J C]]
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[[Category: Pennella MA]]
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[[Category: VanZile, M L]]
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[[Category: Sacchettini JC]]
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[[Category: Dna binding]]
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[[Category: VanZile ML]]
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[[Category: Transcription repressor]]
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[[Category: Transcriptional regulation]]
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[[Category: Winged hth protein]]
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Current revision

Crystal structure of the cyanobacterial metallothionein repressor SmtB in the apo-form

PDB ID 1r1t

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