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2yvk

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==Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis==
==Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis==
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<StructureSection load='2yvk' size='340' side='right' caption='[[2yvk]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='2yvk' size='340' side='right'caption='[[2yvk]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yvk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YVK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yvk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YVK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRU:5-S-METHYL-1-O-PHOSPHONO-5-THIO-D-RIBULOSE'>MRU</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yrf|2yrf]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MRU:5-S-METHYL-1-O-PHOSPHONO-5-THIO-D-RIBULOSE'>MRU</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mtnA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yvk OCA], [https://pdbe.org/2yvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yvk RCSB], [https://www.ebi.ac.uk/pdbsum/2yvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yvk ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/S-methyl-5-thioribose-1-phosphate_isomerase S-methyl-5-thioribose-1-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.23 5.3.1.23] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yvk OCA], [http://pdbe.org/2yvk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yvk RCSB], [http://www.ebi.ac.uk/pdbsum/2yvk PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MTNA_BACSU MTNA_BACSU]] Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<ref>PMID:14551435</ref>
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[https://www.uniprot.org/uniprot/MTNA_BACSU MTNA_BACSU] Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<ref>PMID:14551435</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/2yvk_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yv/2yvk_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus globigii migula 1900]]
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[[Category: Bacillus subtilis]]
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[[Category: S-methyl-5-thioribose-1-phosphate isomerase]]
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[[Category: Large Structures]]
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[[Category: Inoue, T]]
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[[Category: Inoue T]]
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[[Category: Kai, Y]]
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[[Category: Kai Y]]
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[[Category: Matsumura, H]]
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[[Category: Matsumura H]]
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[[Category: Tamura, H]]
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[[Category: Tamura H]]
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[[Category: Isomerase]]
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[[Category: Methionine salvage pathway]]
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Current revision

Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis

PDB ID 2yvk

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