1pvq

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==BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7==
==BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7==
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<StructureSection load='1pvq' size='340' side='right' caption='[[1pvq]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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<StructureSection load='1pvq' size='340' side='right'caption='[[1pvq]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1pvq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpp1 Bpp1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PVQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PVQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1pvq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_P1 Escherichia virus P1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PVQ FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kbu|1kbu]], [[1ma7|1ma7]], [[1crx|1crx]], [[3crx|3crx]], [[1nzb|1nzb]], [[1ouq|1ouq]], [[1f44|1f44]], [[1pvp|1pvp]], [[1pvr|1pvr]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10678 BPP1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pvq OCA], [https://pdbe.org/1pvq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pvq RCSB], [https://www.ebi.ac.uk/pdbsum/1pvq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pvq ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pvq OCA], [http://pdbe.org/1pvq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1pvq RCSB], [http://www.ebi.ac.uk/pdbsum/1pvq PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RECR_BPP1 RECR_BPP1]] Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.
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[https://www.uniprot.org/uniprot/RECR_BPP1 RECR_BPP1] Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/1pvq_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/1pvq_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Resolvase|Resolvase]]
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*[[Resolvase 3D structures|Resolvase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpp1]]
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[[Category: Escherichia virus P1]]
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[[Category: Abel, J]]
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[[Category: Large Structures]]
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[[Category: Baldwin, E P]]
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[[Category: Abel J]]
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[[Category: Gelato, K A]]
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[[Category: Baldwin EP]]
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[[Category: Kim, H]]
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[[Category: Gelato KA]]
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[[Category: Martin, S S]]
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[[Category: Kim H]]
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[[Category: Santoro, S W]]
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[[Category: Martin SS]]
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[[Category: Schultz, P G]]
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[[Category: Santoro SW]]
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[[Category: Cre]]
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[[Category: Schultz PG]]
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[[Category: Cre-loxp recombination]]
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[[Category: Dna]]
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[[Category: Recombinase]]
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[[Category: Recombination-dna complex]]
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Current revision

BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7

PDB ID 1pvq

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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