2r6f

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==Crystal Structure of Bacillus stearothermophilus UvrA==
==Crystal Structure of Bacillus stearothermophilus UvrA==
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<StructureSection load='2r6f' size='340' side='right' caption='[[2r6f]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='2r6f' size='340' side='right'caption='[[2r6f]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2r6f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_stearothermophilus_10 Bacillus stearothermophilus 10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R6F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R6F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2r6f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus_10 Geobacillus stearothermophilus 10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R6F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">uvrA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272567 Bacillus stearothermophilus 10])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r6f OCA], [https://pdbe.org/2r6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r6f RCSB], [https://www.ebi.ac.uk/pdbsum/2r6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r6f ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r6f OCA], [http://pdbe.org/2r6f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r6f RCSB], [http://www.ebi.ac.uk/pdbsum/2r6f PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5KVB6_GEOKA Q5KVB6_GEOKA] The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.[HAMAP-Rule:MF_00205]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/2r6f_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/2r6f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[UvrABC|UvrABC]]
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*[[UvrABC 3D structures|UvrABC 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus stearothermophilus 10]]
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[[Category: Geobacillus stearothermophilus 10]]
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[[Category: Bowman, B R]]
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[[Category: Large Structures]]
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[[Category: Inuzuka, Y]]
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[[Category: Bowman BR]]
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[[Category: Jeruzalmi, D]]
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[[Category: Inuzuka Y]]
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[[Category: Pakotiprapha, D]]
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[[Category: Jeruzalmi D]]
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[[Category: Verdine, G L]]
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[[Category: Pakotiprapha D]]
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[[Category: Abc atpase]]
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[[Category: Verdine GL]]
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[[Category: Atp-binding cassette]]
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[[Category: Dna damage]]
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[[Category: Dna excision]]
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[[Category: Dna repair]]
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[[Category: Dna-binding]]
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[[Category: Excision nuclease]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide excision repair]]
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[[Category: Nucleotide-binding]]
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[[Category: Sos response]]
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[[Category: Uvra]]
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Current revision

Crystal Structure of Bacillus stearothermophilus UvrA

PDB ID 2r6f

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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