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2zy4

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==dodecameric L-aspartate beta-decarboxylase==
==dodecameric L-aspartate beta-decarboxylase==
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<StructureSection load='2zy4' size='340' side='right' caption='[[2zy4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2zy4' size='340' side='right'caption='[[2zy4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zy4]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/'alcaligenes_odorans' 'alcaligenes odorans']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZY4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zy4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_faecalis_subsp._faecalis Alcaligenes faecalis subsp. faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZY4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zy2|2zy2]], [[2zy3|2zy3]], [[2zy5|2zy5]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">asdA-AF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32001 'Alcaligenes odorans'])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zy4 OCA], [https://pdbe.org/2zy4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zy4 RCSB], [https://www.ebi.ac.uk/pdbsum/2zy4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zy4 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_4-decarboxylase Aspartate 4-decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.12 4.1.1.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zy4 OCA], [http://pdbe.org/2zy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2zy4 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ASDA_COMTE ASDA_COMTE]] Bifunctional enzyme that has both L-aspartate decarboxylase and transaminase activity.<ref>PMID:19368885</ref> [PDB:2ZY3]
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[https://www.uniprot.org/uniprot/ASDA_COMTE ASDA_COMTE] Bifunctional enzyme that has both L-aspartate decarboxylase and transaminase activity.<ref>PMID:19368885</ref> [PDB:2ZY3]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/2zy4_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/2zy4_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Aspartate decarboxylase|Aspartate decarboxylase]]
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*[[Aspartate decarboxylase 3D structures|Aspartate decarboxylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Alcaligenes odorans]]
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[[Category: Alcaligenes faecalis subsp. faecalis]]
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[[Category: Aspartate 4-decarboxylase]]
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[[Category: Large Structures]]
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[[Category: Chen, H J]]
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[[Category: Chen H-J]]
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[[Category: Ko, T P]]
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[[Category: Ko T-P]]
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[[Category: Lee, C Y]]
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[[Category: Lee C-Y]]
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[[Category: Wang, A H.J]]
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[[Category: Wang AH-J]]
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[[Category: Wang, N C]]
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[[Category: Wang N-C]]
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[[Category: Aminotransferase]]
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[[Category: Lyase]]
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[[Category: Pyridoxal 5'-phosphate]]
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Current revision

dodecameric L-aspartate beta-decarboxylase

PDB ID 2zy4

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