1e5e

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[[Image:1e5e.gif|left|200px]]
 
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{{Structure
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==METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE==
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|PDB= 1e5e |SIZE=350|CAPTION= <scene name='initialview01'>1e5e</scene>, resolution 2.18&Aring;
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<StructureSection load='1e5e' size='340' side='right'caption='[[1e5e]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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|SITE= <scene name='pdbsite=PLA:Plp+Binding+Site+Chain+A'>PLA</scene> and <scene name='pdbsite=PLB:Plp+Binding+Site+Chain+B'>PLB</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PPJ:N-(HYDROXY{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)NORVALINE'>PPJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1e5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichomonas_vaginalis_G3 Trichomonas vaginalis G3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E5E FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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|GENE= MGL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5722 Trichomonas vaginalis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PPJ:N-(HYDROXY{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)NORVALINE'>PPJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5e OCA], [https://pdbe.org/1e5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e5e RCSB], [https://www.ebi.ac.uk/pdbsum/1e5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e5e ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5e OCA], [http://www.ebi.ac.uk/pdbsum/1e5e PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1e5e RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/A2FEV4_TRIV3 A2FEV4_TRIV3]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/1e5e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e5e ConSurf].
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<div style="clear:both"></div>
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'''METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE'''
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==See Also==
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*[[Methionine gamma-lyase 3D structures|Methionine gamma-lyase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1E5E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Trichomonas_vaginalis Trichomonas vaginalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5E OCA].
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[[Category: Large Structures]]
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[[Category: Methionine gamma-lyase]]
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[[Category: Trichomonas vaginalis G3]]
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[[Category: Single protein]]
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[[Category: Coombs GH]]
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[[Category: Trichomonas vaginalis]]
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[[Category: Goodall G]]
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[[Category: Coombs, G H.]]
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[[Category: Lapthorn AJ]]
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[[Category: Goodall, G.]]
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[[Category: Mottram JC]]
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[[Category: Lapthorn, A J.]]
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[[Category: Mottram, J C.]]
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[[Category: c-s gamma lyase]]
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[[Category: plp-dependent enzyme]]
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[[Category: propargylglycine]]
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[[Category: trichomonas vaginali]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:55:32 2008''
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Current revision

METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE

PDB ID 1e5e

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