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1in6

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==THERMOTOGA MARITIMA RUVB K64R MUTANT==
==THERMOTOGA MARITIMA RUVB K64R MUTANT==
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<StructureSection load='1in6' size='340' side='right' caption='[[1in6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='1in6' size='340' side='right'caption='[[1in6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1in6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IN6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IN6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1in6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IN6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1in4|1in4]], [[1in5|1in5]], [[1in7|1in7]], [[1in8|1in8]], [[1j7k|1j7k]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RuvB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1in6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1in6 OCA], [https://pdbe.org/1in6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1in6 RCSB], [https://www.ebi.ac.uk/pdbsum/1in6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1in6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1in6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1in6 OCA], [http://pdbe.org/1in6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1in6 RCSB], [http://www.ebi.ac.uk/pdbsum/1in6 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RUVB_THEMA RUVB_THEMA]] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity).
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[https://www.uniprot.org/uniprot/RUVB_THEMA RUVB_THEMA] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/in/1in6_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/in/1in6_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Helicase|Helicase]]
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*[[Helicase 3D structures|Helicase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43589]]
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[[Category: Large Structures]]
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[[Category: Clancy, S B]]
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[[Category: Thermotoga maritima]]
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[[Category: Putnam, C D]]
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[[Category: Clancy SB]]
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[[Category: Tainer, J A]]
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[[Category: Putnam CD]]
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[[Category: Tsuruta, H]]
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[[Category: Tainer JA]]
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[[Category: Wetmur, J G]]
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[[Category: Tsuruta H]]
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[[Category: Aaa+-class atpase]]
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[[Category: Wetmur JG]]
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[[Category: Arginine finger]]
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[[Category: Branch migration]]
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[[Category: Dna binding protein]]
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[[Category: Holliday junction]]
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[[Category: Sensor 1]]
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[[Category: Sensor 2]]
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[[Category: Walker some]]
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[[Category: Walker b]]
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[[Category: Winged-helix domain]]
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Current revision

THERMOTOGA MARITIMA RUVB K64R MUTANT

PDB ID 1in6

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