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3eb9

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==Crystal structure of 6-phosphogluconolactonase from trypanosoma brucei complexed with citrate==
==Crystal structure of 6-phosphogluconolactonase from trypanosoma brucei complexed with citrate==
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<StructureSection load='3eb9' size='340' side='right' caption='[[3eb9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='3eb9' size='340' side='right'caption='[[3eb9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3eb9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EB9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EB9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3eb9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EB9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e7f|3e7f]], [[2j0e|2j0e]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">6pgl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma (Trypanozoon) brucei])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb9 OCA], [https://pdbe.org/3eb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eb9 RCSB], [https://www.ebi.ac.uk/pdbsum/3eb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eb9 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gluconolactonase Gluconolactonase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.17 3.1.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3eb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eb9 OCA], [http://pdbe.org/3eb9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3eb9 RCSB], [http://www.ebi.ac.uk/pdbsum/3eb9 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9GRG6_9TRYP Q9GRG6_9TRYP]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb9_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3eb9_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Gluconolactonase]]
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[[Category: Large Structures]]
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[[Category: Delarue, M]]
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[[Category: Duclert-Savatier, N]]
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[[Category: Poggi, L]]
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[[Category: Stoven, V]]
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[[Category: 6-phosphogluconolactonase]]
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[[Category: Catalytic mechanism]]
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[[Category: Hydrolase]]
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[[Category: Pentose phosphate pathway]]
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[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Zinc binding site]]
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[[Category: Delarue M]]
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[[Category: Duclert-Savatier N]]
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[[Category: Poggi L]]
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[[Category: Stoven V]]

Current revision

Crystal structure of 6-phosphogluconolactonase from trypanosoma brucei complexed with citrate

PDB ID 3eb9

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