This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1qx8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:57, 23 August 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of a five-residue deletion mutant of the Rop protein==
==Crystal structure of a five-residue deletion mutant of the Rop protein==
-
<StructureSection load='1qx8' size='340' side='right' caption='[[1qx8]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
+
<StructureSection load='1qx8' size='340' side='right'caption='[[1qx8]], [[Resolution|resolution]] 2.02&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1qx8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QX8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QX8 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1qx8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QX8 FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rop|1rop]], [[1rpo|1rpo]], [[1b6q|1b6q]], [[1gmg|1gmg]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.02&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rop ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qx8 OCA], [https://pdbe.org/1qx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qx8 RCSB], [https://www.ebi.ac.uk/pdbsum/1qx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qx8 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qx8 OCA], [http://pdbe.org/1qx8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qx8 RCSB], [http://www.ebi.ac.uk/pdbsum/1qx8 PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX]] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
+
[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qx/1qx8_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qx/1qx8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 35: Line 35:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bacillus coli migula 1895]]
+
[[Category: Escherichia coli]]
-
[[Category: Cesareni, G]]
+
[[Category: Large Structures]]
-
[[Category: Glykos, N M]]
+
[[Category: Cesareni G]]
-
[[Category: Kokkinidis, M]]
+
[[Category: Glykos NM]]
-
[[Category: Kotsifaki, D]]
+
[[Category: Kokkinidis M]]
-
[[Category: Papanikolaou, Y]]
+
[[Category: Kotsifaki D]]
-
[[Category: Vlassi, M]]
+
[[Category: Papanikolaou Y]]
-
[[Category: Initiation of transcription]]
+
[[Category: Vlassi M]]
-
[[Category: Replication]]
+
-
[[Category: Rna primer]]
+
-
[[Category: Transcription]]
+
-
[[Category: X-ray]]
+

Current revision

Crystal structure of a five-residue deletion mutant of the Rop protein

PDB ID 1qx8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qx8"
Personal tools