3lx3

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==Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS) in complex with xanthopterin==
==Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS) in complex with xanthopterin==
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<StructureSection load='3lx3' size='340' side='right' caption='[[3lx3]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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<StructureSection load='3lx3' size='340' side='right'caption='[[3lx3]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3lx3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plavi Plavi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LX3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LX3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3lx3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LX3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XTN:2-AMINO-1,5-DIHYDROPTERIDINE-4,6-DIONE'>XTN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2a0s|2a0s]], [[1y13|1y13]], [[3lze|3lze]], [[3m0n|3m0n]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XTN:2-AMINO-1,5-DIHYDROPTERIDINE-4,6-DIONE'>XTN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PVX_114505 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5855 PLAVI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lx3 OCA], [https://pdbe.org/3lx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lx3 RCSB], [https://www.ebi.ac.uk/pdbsum/3lx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lx3 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-pyruvoyltetrahydropterin_synthase 6-pyruvoyltetrahydropterin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.12 4.2.3.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lx3 OCA], [http://pdbe.org/3lx3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lx3 RCSB], [http://www.ebi.ac.uk/pdbsum/3lx3 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A5K2B2_PLAVS A5K2B2_PLAVS]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lx/3lx3_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lx/3lx3_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 6-pyruvoyltetrahydropterin synthase]]
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[[Category: Large Structures]]
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[[Category: Plavi]]
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[[Category: Plasmodium vivax]]
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[[Category: Larson, E T]]
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[[Category: Larson ET]]
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[[Category: Structural genomic]]
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[[Category: Merritt EA]]
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[[Category: Merritt, E A]]
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[[Category: Biosynthetic protein]]
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[[Category: Folate biosynthesis]]
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[[Category: Metal-binding]]
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[[Category: Msgpp]]
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[[Category: Ptp synthase]]
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[[Category: Ptp]]
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[[Category: Pt]]
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[[Category: Tetrahydrobiopterin biosynthesis]]
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Current revision

Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS) in complex with xanthopterin

PDB ID 3lx3

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