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1uw5

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==STRUCTURE OF PITP-ALPHA COMPLEXED TO PHOSPHATIDYLINOSITOL==
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<StructureSection load='1uw5' size='340' side='right' caption='[[1uw5]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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==Structure of PITP-alpha complexed to phosphatidylinositol==
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<StructureSection load='1uw5' size='340' side='right'caption='[[1uw5]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1uw5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UW5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UW5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1uw5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UW5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PIE:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL'>PIE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PIE:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL'>PIE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uw5 OCA], [http://pdbe.org/1uw5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uw5 RCSB], [http://www.ebi.ac.uk/pdbsum/1uw5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uw5 OCA], [https://pdbe.org/1uw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uw5 RCSB], [https://www.ebi.ac.uk/pdbsum/1uw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uw5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PIPNA_HUMAN PIPNA_HUMAN]] Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
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[https://www.uniprot.org/uniprot/PIPNA_HUMAN PIPNA_HUMAN] Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/1uw5_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/1uw5_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Cockcroft, S]]
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[[Category: Large Structures]]
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[[Category: Mcdonald, N Q]]
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[[Category: Cockcroft S]]
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[[Category: Murray-Rust, J]]
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[[Category: McDonald NQ]]
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[[Category: Skippen, A]]
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[[Category: Murray-Rust J]]
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[[Category: Tilley, S J]]
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[[Category: Skippen A]]
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[[Category: Lipid-binding]]
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[[Category: Tilley SJ]]
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[[Category: Transfer protein]]
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[[Category: Transport]]
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Current revision

Structure of PITP-alpha complexed to phosphatidylinositol

PDB ID 1uw5

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