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1lpc

From Proteopedia

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==HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT (COMPLEX WITH CYCLIC AMP)==
==HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT (COMPLEX WITH CYCLIC AMP)==
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<StructureSection load='1lpc' size='340' side='right' caption='[[1lpc]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='1lpc' size='340' side='right'caption='[[1lpc]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1lpc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Carnation Carnation]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LPC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1lpc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dianthus_caryophyllus Dianthus caryophyllus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LPC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lp8|1lp8]], [[1lpd|1lpd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lpc OCA], [https://pdbe.org/1lpc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lpc RCSB], [https://www.ebi.ac.uk/pdbsum/1lpc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lpc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lpc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lpc OCA], [http://pdbe.org/1lpc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lpc RCSB], [http://www.ebi.ac.uk/pdbsum/1lpc PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RIP0_DIACA RIP0_DIACA]] Single-chain ribosome-inactivating protein.
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[https://www.uniprot.org/uniprot/RIP0_DIACA RIP0_DIACA] Single-chain ribosome-inactivating protein.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/1lpc_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/1lpc_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Ribosome inactivating protein|Ribosome inactivating protein]]
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*[[Ribosome inactivating protein 3D structures|Ribosome inactivating protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Carnation]]
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[[Category: Dianthus caryophyllus]]
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[[Category: RRNA N-glycosylase]]
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[[Category: Large Structures]]
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[[Category: Kurinov, I V]]
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[[Category: Kurinov IV]]
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[[Category: Rajamohan, F]]
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[[Category: Rajamohan F]]
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[[Category: Uckun, F M]]
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[[Category: Uckun FM]]
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[[Category: Anti-hiv agent]]
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[[Category: Antiviral protein]]
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[[Category: Dianthin antiviral protein]]
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[[Category: Hiv-1 integrase inhibitor]]
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[[Category: Polynucleotide:adenosine glycosidase]]
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[[Category: Ribosome inactivating protein]]
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Current revision

HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT (COMPLEX WITH CYCLIC AMP)

PDB ID 1lpc

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