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| - | [[Image:1ehv.gif|left|200px]] | |
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| - | {{Structure
| + | ==A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE== |
| - | |PDB= 1ehv |SIZE=350|CAPTION= <scene name='initialview01'>1ehv</scene>, resolution 1.8Å
| + | <StructureSection load='1ehv' size='340' side='right'caption='[[1ehv]], [[Resolution|resolution]] 1.80Å' scene=''> |
| - | |SITE=
| + | == Structural highlights == |
| - | |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>
| + | <table><tr><td colspan='2'>[[1ehv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EHV FirstGlance]. <br> |
| - | |ACTIVITY=
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | |GENE=
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ehv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ehv OCA], [https://pdbe.org/1ehv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ehv RCSB], [https://www.ebi.ac.uk/pdbsum/1ehv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ehv ProSAT]</span></td></tr> |
| - | |DOMAIN=
| + | </table> |
| - | |RELATEDENTRY=
| + | __TOC__ |
| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ehv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ehv OCA], [http://www.ebi.ac.uk/pdbsum/1ehv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ehv RCSB]</span>
| + | </StructureSection> |
| - | }}
| + | [[Category: Large Structures]] |
| - | | + | [[Category: Johansson EM]] |
| - | '''A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE'''
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| - | | + | |
| - | ==Overview==
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| - | The dodecanucleotide d(CGCGAATTCGCG) has been crystallised in the space group P3(2)12, representing a new crystal form for this sequence. The structure has been solved by molecular replacement and refined at 1.8 A resolution. The present structure contrasts with previous ones for this sequence since it is situated on a crystallographic 2-fold axis, and the crystal symmetry reflects the palindromic nature of this sequence. Some features accord with previous observations, notably that the minor groove is hydrated with a continuous spine of solvent. There is no evidence of alkali metal ions within this spine. The minor groove retains its narrow width, although it is now symmetric and extends over the A/T tract. Various base and base-pair morphological parameters have been examined. Their values do not show significant correlations with earlier reports, suggesting that crystal packing effects on them are more dominant than has been hitherto realised.
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| - | ==About this Structure==
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| - | 1EHV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EHV OCA].
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| - | ==Reference==
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| - | A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure., Johansson E, Parkinson G, Neidle S, J Mol Biol. 2000 Jul 14;300(3):551-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10884351 10884351]
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| - | [[Category: Protein complex]]
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| - | [[Category: Johansson, E M.]]
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| - | [[Category: crystal packing]] | + | |
| - | [[Category: dickerson dodecamer]] | + | |
| - | [[Category: dna]]
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:02:51 2008''
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