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3f3c

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==Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium==
==Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium==
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<StructureSection load='3f3c' size='340' side='right' caption='[[3f3c]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3f3c' size='340' side='right'caption='[[3f3c]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3f3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3F3C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3f3c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F3C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PFF:4-FLUORO-L-PHENYLALANINE'>PFF</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2a65|2a65]], [[2qei|2qei]], [[3f3a|3f3a]], [[3f3d|3f3d]], [[3f3e|3f3e]], [[3f48|3f48]], [[3f4i|3f4i]], [[3f4j|3f4j]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PFF:4-FLUORO-L-PHENYLALANINE'>PFF</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">snf, aq_2077 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f3c OCA], [https://pdbe.org/3f3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f3c RCSB], [https://www.ebi.ac.uk/pdbsum/3f3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f3c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f3c OCA], [http://pdbe.org/3f3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3f3c RCSB], [http://www.ebi.ac.uk/pdbsum/3f3c PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O67854_AQUAE O67854_AQUAE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f3/3f3c_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f3/3f3c_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Leucine transporter|Leucine transporter]]
*[[Leucine transporter|Leucine transporter]]
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*[[Symporter 3D structures|Symporter 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aquifex aeolicus huber and stetter 2001]]
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[[Category: Aquifex aeolicus]]
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[[Category: Gouaux, E]]
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[[Category: Large Structures]]
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[[Category: Piscitelli, C L]]
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[[Category: Gouaux E]]
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[[Category: Singh, S K]]
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[[Category: Piscitelli CL]]
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[[Category: Yamashita, A]]
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[[Category: Singh SK]]
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[[Category: Nss]]
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[[Category: Yamashita A]]
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[[Category: Slc6]]
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[[Category: Sodium-coupled]]
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[[Category: Symport]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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[[Category: Transport protein]]
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[[Category: Transporter]]
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Current revision

Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium

PDB ID 3f3c

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