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2jjr

From Proteopedia

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==V232K, N236D-TRICHOSANTHIN==
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<StructureSection load='2jjr' size='340' side='right' caption='[[2jjr]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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==V232K, N236D-trichosanthin==
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<StructureSection load='2jjr' size='340' side='right'caption='[[2jjr]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jjr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chinese_cucumber Chinese cucumber]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JJR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JJR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jjr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JJR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TAM:TRIS(HYDROXYETHYL)AMINOMETHANE'>TAM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mrk|1mrk]], [[1giu|1giu]], [[1tcs|1tcs]], [[1nli|1nli]], [[2vs6|2vs6]], [[1j4g|1j4g]], [[1mrj|1mrj]], [[2jdl|2jdl]], [[1gis|1gis]], [[1qd2|1qd2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TAM:TRIS(HYDROXYETHYL)AMINOMETHANE'>TAM</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jjr OCA], [https://pdbe.org/2jjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jjr RCSB], [https://www.ebi.ac.uk/pdbsum/2jjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jjr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jjr OCA], [http://pdbe.org/2jjr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jjr RCSB], [http://www.ebi.ac.uk/pdbsum/2jjr PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RIPT_TRIKI RIPT_TRIKI]] Inactivates eukaryotic 60S ribosomal subunits.
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[https://www.uniprot.org/uniprot/RIPT_TRIKI RIPT_TRIKI] Inactivates eukaryotic 60S ribosomal subunits.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/2jjr_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/2jjr_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2jjr" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2jjr" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribosome inactivating protein 3D structures|Ribosome inactivating protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chinese cucumber]]
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[[Category: Large Structures]]
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[[Category: RRNA N-glycosylase]]
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[[Category: Trichosanthes kirilowii]]
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[[Category: Au, S W]]
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[[Category: Au SW]]
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[[Category: Ma, M K]]
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[[Category: Ma MK]]
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[[Category: Mak, A N]]
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[[Category: Mak AN]]
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[[Category: Shaw, P C]]
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[[Category: Shaw PC]]
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[[Category: Too, P H]]
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[[Category: Too PH]]
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[[Category: Tung, C K]]
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[[Category: Tung CK]]
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[[Category: Wong, K B]]
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[[Category: Wong KB]]
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[[Category: Zhu, G]]
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[[Category: Zhu G]]
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[[Category: Antiviral protein]]
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[[Category: Hydrolase]]
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[[Category: Plant defense]]
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[[Category: Protein synthesis inhibitor]]
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[[Category: Tc]]
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[[Category: Toxin]]
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Current revision

V232K, N236D-trichosanthin

PDB ID 2jjr

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