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2z8h

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==Structure of mouse Bach1 BTB domain==
==Structure of mouse Bach1 BTB domain==
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<StructureSection load='2z8h' size='340' side='right' caption='[[2z8h]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='2z8h' size='340' side='right'caption='[[2z8h]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2z8h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z8H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z8H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2z8h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z8H FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Bach1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z8h OCA], [http://pdbe.org/2z8h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z8h RCSB], [http://www.ebi.ac.uk/pdbsum/2z8h PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z8h OCA], [https://pdbe.org/2z8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z8h RCSB], [https://www.ebi.ac.uk/pdbsum/2z8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z8h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BACH1_MOUSE BACH1_MOUSE]] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
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[https://www.uniprot.org/uniprot/BACH1_MOUSE BACH1_MOUSE] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/2z8h_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/2z8h_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Ito, N]]
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[[Category: Mus musculus]]
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[[Category: Murayama, K]]
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[[Category: Ito N]]
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[[Category: Activator]]
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[[Category: Murayama K]]
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[[Category: Btb]]
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[[Category: Disulfide bond]]
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[[Category: Dna-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphorylation]]
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[[Category: Poz]]
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[[Category: Repressor]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Current revision

Structure of mouse Bach1 BTB domain

PDB ID 2z8h

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