2cit

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==STRUCTURE OF THE COVALENT INTERMEDIATE OF A FAMILY 26 LICHENASE==
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<StructureSection load='2cit' size='340' side='right' caption='[[2cit]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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==Structure of the covalent intermediate of a family 26 lichenase==
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<StructureSection load='2cit' size='340' side='right'caption='[[2cit]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cit]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27405 Atcc 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CIT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cit]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CIT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=G2F:2-DEOXY-2-FLUORO-ALPHA-D-GLUCOPYRANOSE'>G2F</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1v0a|1v0a]], [[2bv9|2bv9]], [[2bvd|2bvd]], [[2cip|2cip]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=G2F:2-DEOXY-2-FLUORO-ALPHA-D-GLUCOPYRANOSE'>G2F</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulase Cellulase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cit OCA], [https://pdbe.org/2cit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cit RCSB], [https://www.ebi.ac.uk/pdbsum/2cit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cit ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cit OCA], [http://pdbe.org/2cit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cit RCSB], [http://www.ebi.ac.uk/pdbsum/2cit PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GUNH_ACET2 GUNH_ACET2] This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/2cit_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ci/2cit_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Glucanase|Glucanase]]
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*[[Glucanase 3D structures|Glucanase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 27405]]
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[[Category: Acetivibrio thermocellus]]
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[[Category: Cellulase]]
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[[Category: Large Structures]]
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[[Category: Davies, G J]]
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[[Category: Davies GJ]]
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[[Category: Gilbert, H J]]
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[[Category: Gilbert HJ]]
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[[Category: Money, V A]]
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[[Category: Money VA]]
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[[Category: Scaffidi, A]]
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[[Category: Scaffidi A]]
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[[Category: Smith, N L]]
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[[Category: Smith NL]]
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[[Category: Stick, R V]]
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[[Category: Stick RV]]
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[[Category: Carbohydrate metabolism]]
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[[Category: Cellulose degradation]]
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[[Category: Glycosidase]]
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[[Category: Glycoside hydrolase]]
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[[Category: Hydrolase]]
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[[Category: Lichenase]]
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[[Category: Michaelis complex]]
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[[Category: Polysaccharide degradation]]
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Current revision

Structure of the covalent intermediate of a family 26 lichenase

PDB ID 2cit

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