This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2v77

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:08, 13 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
==CRYSTAL STRUCTURE OF HUMAN CARBOXYPEPTIDASE A1==
+
 
-
<StructureSection load='2v77' size='340' side='right' caption='[[2v77]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+
==Crystal Structure of Human Carboxypeptidase A1==
 +
<StructureSection load='2v77' size='340' side='right'caption='[[2v77]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2v77]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V77 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2v77]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V77 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=PAY:OCTANE-1,3,5,7-TETRACARBOXYLIC+ACID'>PAY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.603&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.14.17.1 3.14.17.1] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=PAY:OCTANE-1,3,5,7-TETRACARBOXYLIC+ACID'>PAY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v77 OCA], [http://pdbe.org/2v77 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v77 RCSB], [http://www.ebi.ac.uk/pdbsum/2v77 PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v77 OCA], [https://pdbe.org/2v77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v77 RCSB], [https://www.ebi.ac.uk/pdbsum/2v77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v77 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>
+
[https://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v7/2v77_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v7/2v77_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 30: Line 31:
==See Also==
==See Also==
-
*[[Carboxypeptidase|Carboxypeptidase]]
+
*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Hydrolase]]
+
[[Category: Large Structures]]
-
[[Category: Aviles, F X]]
+
[[Category: Aviles FX]]
-
[[Category: Comellas-Bigler, M]]
+
[[Category: Comellas-Bigler M]]
-
[[Category: Fernandez, D]]
+
[[Category: Fernandez D]]
-
[[Category: Fernandez-Recio, J]]
+
[[Category: Fernandez-Recio J]]
-
[[Category: Pallares, I]]
+
[[Category: Pallares I]]
-
[[Category: Vendrell, J]]
+
[[Category: Vendrell J]]
-
[[Category: Ventura, S]]
+
[[Category: Ventura S]]
-
[[Category: Carboxypeptidase]]
+
-
[[Category: Metal-binding]]
+
-
[[Category: Metalloprotease]]
+
-
[[Category: Protease]]
+
-
[[Category: Protein degradation]]
+
-
[[Category: Secreted]]
+
-
[[Category: Zymogen]]
+

Current revision

Crystal Structure of Human Carboxypeptidase A1

PDB ID 2v77

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2v77"
Personal tools