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2bv6

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==CRYSTAL STRUCTURE OF MGRA, A GLOBAL REGULATOR AND MAJOR VIRULENCE DETERMINANT IN STAPHYLOCOCCUS AUREUS==
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<StructureSection load='2bv6' size='340' side='right' caption='[[2bv6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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==Crystal structure of MgrA, a global regulator and major virulence determinant in Staphylococcus aureus==
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<StructureSection load='2bv6' size='340' side='right'caption='[[2bv6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bv6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BV6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bv6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BV6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv6 OCA], [http://pdbe.org/2bv6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bv6 RCSB], [http://www.ebi.ac.uk/pdbsum/2bv6 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv6 OCA], [https://pdbe.org/2bv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bv6 RCSB], [https://www.ebi.ac.uk/pdbsum/2bv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bv6 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MGRA_STAAU MGRA_STAAU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bv6_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bv6_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2bv6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2bv6" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bae, T]]
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[[Category: Large Structures]]
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[[Category: Chen, P R]]
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[[Category: Staphylococcus aureus]]
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[[Category: Duguid, E M]]
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[[Category: Bae T]]
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[[Category: He, C]]
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[[Category: Chen PR]]
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[[Category: Rice, P A]]
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[[Category: Duguid EM]]
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[[Category: Schneewind, O]]
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[[Category: He C]]
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[[Category: Williams, W A]]
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[[Category: Rice PA]]
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[[Category: Multidrug resistance regulator]]
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[[Category: Schneewind O]]
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[[Category: Transcriptional factor]]
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[[Category: Williams WA]]
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[[Category: Transcriptional regulator]]
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[[Category: Virulence determinant]]
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Current revision

Crystal structure of MgrA, a global regulator and major virulence determinant in Staphylococcus aureus

PDB ID 2bv6

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