Enzymes: enzyme-substrate complex

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[[es:Enzymes: enzyme-substrate complex (spanish)]]
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<Structure load='4ald' size='800' frame='true' align='right' caption='Fructosa-bifosfato aldolasa (PDB [[4ald]])' scene='60/603296/F2pa/4' />
<Structure load='4ald' size='800' frame='true' align='right' caption='Fructosa-bifosfato aldolasa (PDB [[4ald]])' scene='60/603296/F2pa/4' />
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:::This <scene name='60/603296/F2pa/4'>ribbon model</scene> shows secondary structures in '''Fructose biphosphate aldolase''' molecule.
:::This <scene name='60/603296/F2pa/4'>ribbon model</scene> shows secondary structures in '''Fructose biphosphate aldolase''' molecule.
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:::This <scene name='60/603296/F2pa/3'>wireframe model</scene> shows the polypeptide chain skeleton and R groups.
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:::This <scene name='60/603296/F2pa/3'>wireframe model</scene> shows the polypeptide chain skeleton and amino acids R groups.
:::The polypeptide chain of this enzyme consist of <scene name='60/603296/F2pa/17'>363 amino acid residues</scene>.
:::The polypeptide chain of this enzyme consist of <scene name='60/603296/F2pa/17'>363 amino acid residues</scene>.
:::Now, we are going to <scene name='60/603296/F2pa/5'>soften colors</scene> to highligth the enzyme <scene name='60/603296/F2pa/6'>active site</scene>
:::Now, we are going to <scene name='60/603296/F2pa/5'>soften colors</scene> to highligth the enzyme <scene name='60/603296/F2pa/6'>active site</scene>

Current revision

Fructosa-bifosfato aldolasa (PDB 4ald)

Drag the structure with the mouse to rotate






  • Enzyme: Fructose biphosphate aldolase
  • Substrate: fructose-1,6-biphosphate
  • Products: glyceraldehyde-3-phosphate and dihydroxiacetone-phosphate.
This shows secondary structures in Fructose biphosphate aldolase molecule.
This shows the polypeptide chain skeleton and amino acids R groups.
The polypeptide chain of this enzyme consist of .
Now, we are going to to highligth the enzyme
Active site is surrounded by
, i.e., fructose-1,6-biphosphate. fits into active site.
In this , fit between active site and substrate is best seen.
Zoom out to see a whole view.


All models we have analyzed show a of fructose biphosphate aldolase. Really, this enzyme is a oligomeric protein composed of four subunits that perform a .

References

This page is based on the Proteopedia file 4ald.

Proteopedia Page Contributors and Editors (what is this?)

Alejandro Porto

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