2x4f
From Proteopedia
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==The Crystal Structure of the human myosin light chain kinase LOC340156.== | ==The Crystal Structure of the human myosin light chain kinase LOC340156.== | ||
| - | <StructureSection load='2x4f' size='340' side='right' caption='[[2x4f]], [[Resolution|resolution]] 2.67Å' scene=''> | + | <StructureSection load='2x4f' size='340' side='right'caption='[[2x4f]], [[Resolution|resolution]] 2.67Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2x4f]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2x4f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X4F FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16X:4-(2-AMINO-4-METHYL-1,3-THIAZOL-5-YL)-N-(3-DIOXAZIRIDIN-3-YLPHENYL)PYRIMIDIN-2-AMINE'>16X</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.67Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=16X:4-(2-AMINO-4-METHYL-1,3-THIAZOL-5-YL)-N-(3-DIOXAZIRIDIN-3-YLPHENYL)PYRIMIDIN-2-AMINE'>16X</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x4f OCA], [https://pdbe.org/2x4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x4f RCSB], [https://www.ebi.ac.uk/pdbsum/2x4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x4f ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MYLK4_HUMAN MYLK4_HUMAN] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/2x4f_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/2x4f_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Chaikuad | + | [[Category: Chaikuad A]] |
| - | [[Category: Cocking | + | [[Category: Cocking R]] |
| - | [[Category: Daga | + | [[Category: Daga N]] |
| - | + | [[Category: Edwards AM]] | |
| - | [[Category: Edwards | + | [[Category: Elkins JM]] |
| - | [[Category: Elkins | + | [[Category: Fedorov O]] |
| - | [[Category: Fedorov | + | [[Category: Gileadi O]] |
| - | [[Category: Gileadi | + | [[Category: Knapp S]] |
| - | [[Category: Knapp | + | [[Category: Krojer T]] |
| - | [[Category: Krojer | + | [[Category: Mahajan P]] |
| - | [[Category: Mahajan | + | [[Category: Muniz JRC]] |
| - | [[Category: Muniz | + | [[Category: Rellos P]] |
| - | [[Category: Rellos | + | [[Category: Shrestha B]] |
| - | [[Category: Shrestha | + | [[Category: Ugochukwu E]] |
| - | [[Category: Ugochukwu | + | [[Category: Wang J]] |
| - | [[Category: Wang | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Yue W]] |
| - | [[Category: Yue | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
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Current revision
The Crystal Structure of the human myosin light chain kinase LOC340156.
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Chaikuad A | Cocking R | Daga N | Edwards AM | Elkins JM | Fedorov O | Gileadi O | Knapp S | Krojer T | Mahajan P | Muniz JRC | Rellos P | Shrestha B | Ugochukwu E | Wang J | Weigelt J | Yue W | Von Delft F
