1k47

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==Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)==
==Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)==
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<StructureSection load='1k47' size='340' side='right' caption='[[1k47]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
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<StructureSection load='1k47' size='340' side='right'caption='[[1k47]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1k47]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Strr6 Strr6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K47 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K47 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1k47]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K47 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K47 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fi4|1fi4]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mvaK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=171101 STRR6])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k47 OCA], [https://pdbe.org/1k47 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k47 RCSB], [https://www.ebi.ac.uk/pdbsum/1k47 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k47 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1k47 TOPSAN]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphomevalonate_kinase Phosphomevalonate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.2 2.7.4.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k47 OCA], [http://pdbe.org/1k47 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1k47 RCSB], [http://www.ebi.ac.uk/pdbsum/1k47 PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/1k47 TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8DR49_STRR6 Q8DR49_STRR6]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/1k47_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/1k47_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Phosphomevalonate kinase]]
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[[Category: Large Structures]]
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[[Category: Strr6]]
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[[Category: Streptococcus pneumoniae R6]]
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[[Category: Bonanno, J B]]
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[[Category: Bonanno JB]]
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[[Category: Burley, S K]]
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[[Category: Burley SK]]
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[[Category: Structural genomic]]
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[[Category: Romanowski MJ]]
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[[Category: Romanowski, M J]]
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[[Category: Alpha/beta single domain belonging to the ghmp kinase superfamily]]
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[[Category: Mvak2]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)

PDB ID 1k47

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