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2c4k
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2c4k' size='340' side='right' caption='[[2c4k]], [[Resolution|resolution]] 2.65Å' scene=''> | + | ==Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39)== |
| + | <StructureSection load='2c4k' size='340' side='right'caption='[[2c4k]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2c4k]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2c4k]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C4K FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TAM:TRIS(HYDROXYETHYL)AMINOMETHANE'>TAM</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TAM:TRIS(HYDROXYETHYL)AMINOMETHANE'>TAM</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c4k OCA], [https://pdbe.org/2c4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c4k RCSB], [https://www.ebi.ac.uk/pdbsum/2c4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c4k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KPRA_HUMAN KPRA_HUMAN] Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c4/2c4k_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c4/2c4k_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith C]] |
| - | [[Category: Berglund | + | [[Category: Berglund H]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Ehn | + | [[Category: Ehn M]] |
| - | [[Category: Flodin | + | [[Category: Flodin S]] |
| - | [[Category: Graslund | + | [[Category: Graslund S]] |
| - | [[Category: Hallberg | + | [[Category: Hallberg BM]] |
| - | [[Category: Hammarstrom | + | [[Category: Hammarstrom M]] |
| - | [[Category: Kotenyova | + | [[Category: Holmberg Schiavone L]] |
| - | [[Category: Kursula | + | [[Category: Kotenyova T]] |
| - | [[Category: Nilsson-Ehle | + | [[Category: Kursula P]] |
| - | [[Category: Nordlund | + | [[Category: Nilsson-Ehle P]] |
| - | [[Category: Ogg | + | [[Category: Nordlund P]] |
| - | [[Category: Persson | + | [[Category: Ogg D]] |
| - | [[Category: Sagemark | + | [[Category: Persson C]] |
| - | + | [[Category: Sagemark J]] | |
| - | [[Category: Schuler | + | [[Category: Schuler H]] |
| - | [[Category: Stenmark | + | [[Category: Stenmark P]] |
| - | [[Category: Sundstrom | + | [[Category: Sundstrom M]] |
| - | [[Category: Thorsell | + | [[Category: Thorsell AG]] |
| - | [[Category: | + | [[Category: Van Den Berg S]] |
| - | [[Category: | + | [[Category: Weigelt J]] |
| - | + | ||
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Current revision
Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39)
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Berglund H | Edwards A | Ehn M | Flodin S | Graslund S | Hallberg BM | Hammarstrom M | Holmberg Schiavone L | Kotenyova T | Kursula P | Nilsson-Ehle P | Nordlund P | Ogg D | Persson C | Sagemark J | Schuler H | Stenmark P | Sundstrom M | Thorsell AG | Van Den Berg S | Weigelt J
