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1ys6

From Proteopedia

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==Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis==
==Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis==
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<StructureSection load='1ys6' size='340' side='right' caption='[[1ys6]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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<StructureSection load='1ys6' size='340' side='right'caption='[[1ys6]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ys6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YS6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ys6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YS6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ys3|1ys3]], [[1ys7|1ys7]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ys6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys6 OCA], [http://pdbe.org/1ys6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ys6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ys6 PDBsum], [http://www.topsan.org/Proteins/XMTB/1ys6 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ys6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys6 OCA], [https://pdbe.org/1ys6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ys6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ys6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ys6 ProSAT], [https://www.topsan.org/Proteins/XMTB/1ys6 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRRA_MYCTU PRRA_MYCTU]] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium.
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[https://www.uniprot.org/uniprot/PRRA_MYCTU PRRA_MYCTU] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/1ys6_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/1ys6_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Response regulator|Response regulator]]
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*[[Response regulator 3D structure|Response regulator 3D structure]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Nowak, E]]
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[[Category: Large Structures]]
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[[Category: Panjikar, S]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Tucker, P]]
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[[Category: Nowak E]]
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[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project]]
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[[Category: Panjikar S]]
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[[Category: Dna binding domain]]
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[[Category: Tucker P]]
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[[Category: Mycobacterium tuberculosis structural proteomics project]]
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[[Category: Response regulator protein]]
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[[Category: Structural genomic]]
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[[Category: Transcription regulator]]
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[[Category: Xmtb]]
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Current revision

Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis

PDB ID 1ys6

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