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2dk4

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==Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)==
==Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)==
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<StructureSection load='2dk4' size='340' side='right' caption='[[2dk4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dk4' size='340' side='right'caption='[[2dk4]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dk4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DK4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dk4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DK4 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRPF18, HPRP18 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk4 OCA], [http://pdbe.org/2dk4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dk4 RCSB], [http://www.ebi.ac.uk/pdbsum/2dk4 PDBsum], [http://www.topsan.org/Proteins/RSGI/2dk4 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dk4 OCA], [https://pdbe.org/2dk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dk4 RCSB], [https://www.ebi.ac.uk/pdbsum/2dk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dk4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dk4 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRP18_HUMAN PRP18_HUMAN]] Participates in the second step of pre-mRNA splicing.<ref>PMID:9000057</ref>
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[https://www.uniprot.org/uniprot/PRP18_HUMAN PRP18_HUMAN] Participates in the second step of pre-mRNA splicing.<ref>PMID:9000057</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dk4_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dk4_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Pre-mRNA-splicing factor|Pre-mRNA-splicing factor]]
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*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: He, F]]
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[[Category: Large Structures]]
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[[Category: Inoue, M]]
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[[Category: He F]]
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[[Category: Kigawa, T]]
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[[Category: Inoue M]]
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[[Category: Muto, Y]]
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[[Category: Kigawa T]]
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[[Category: Structural genomic]]
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[[Category: Muto Y]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T]]
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[[Category: Terada T]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Gene regulation]]
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[[Category: Hprp18]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Pre-mrna splicing factor 18]]
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[[Category: Rsgi]]
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[[Category: Sfm domain]]
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Current revision

Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18)

PDB ID 2dk4

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