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1gn3

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==H145Q MUTANT OF MYCOBACTERIUM TUBERCULOSIS IRON-SUPEROXIDE DISMUTASE.==
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<StructureSection load='1gn3' size='340' side='right' caption='[[1gn3]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
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==H145Q mutant of Mycobacterium tuberculosis iron-superoxide dismutase.==
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<StructureSection load='1gn3' size='340' side='right'caption='[[1gn3]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1gn3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GN3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GN3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1gn3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GN3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gn2|1gn2]], [[1gn4|1gn4]], [[1gn6|1gn6]], [[1ids|1ids]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gn3 OCA], [https://pdbe.org/1gn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gn3 RCSB], [https://www.ebi.ac.uk/pdbsum/1gn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gn3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gn3 OCA], [http://pdbe.org/1gn3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gn3 RCSB], [http://www.ebi.ac.uk/pdbsum/1gn3 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SODF_MYCTU SODF_MYCTU]] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
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[https://www.uniprot.org/uniprot/SODF_MYCTU SODF_MYCTU] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/1gn3_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/1gn3_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Superoxide Dismutase|Superoxide Dismutase]]
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Superoxide dismutase]]
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[[Category: Large Structures]]
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[[Category: Badasso, M O]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Bunting, K A]]
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[[Category: Badasso MO]]
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[[Category: Cooper, J B]]
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[[Category: Bunting KA]]
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[[Category: Newton, M]]
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[[Category: Cooper JB]]
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[[Category: Tickle, I J]]
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[[Category: Newton M]]
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[[Category: Wood, S P]]
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[[Category: Tickle IJ]]
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[[Category: Young, D B]]
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[[Category: Wood SP]]
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[[Category: Zhang, Y]]
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[[Category: Young DB]]
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[[Category: Oxidoreductase]]
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[[Category: Zhang Y]]

Current revision

H145Q mutant of Mycobacterium tuberculosis iron-superoxide dismutase.

PDB ID 1gn3

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