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1f1f

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[[Image:1f1f.gif|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF CYTOCHROME C6 FROM ARTHROSPIRA MAXIMA==
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|PDB= 1f1f |SIZE=350|CAPTION= <scene name='initialview01'>1f1f</scene>, resolution 2.7&Aring;
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<StructureSection load='1f1f' size='340' side='right'caption='[[1f1f]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>
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<table><tr><td colspan='2'>[[1f1f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Limnospira_maxima Limnospira maxima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F1F FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f1f OCA], [https://pdbe.org/1f1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f1f RCSB], [https://www.ebi.ac.uk/pdbsum/1f1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f1f ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1cyi|1CYI]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f1f OCA], [http://www.ebi.ac.uk/pdbsum/1f1f PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1f1f RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/CYC6_LIMMA CYC6_LIMMA] Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
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== Evolutionary Conservation ==
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'''CRYSTAL STRUCTURE OF CYTOCHROME C6 FROM ARTHROSPIRA MAXIMA'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==Overview==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f1/1f1f_consurf.spt"</scriptWhenChecked>
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Cytochrome c(6) and cytochrome c-549 are small (89 and 130 amino acids, respectively) monoheme cytochromes that function in photosynthesis. They appear to have descended relatively recently from the same ancestral gene but have diverged to carry out very different functional roles, underscored by the large difference between their midpoint potentials of nearly 600 mV. We have determined the X-ray crystal structures of both proteins isolated from the cyanobacterium Arthrospira maxima. The two structures are remarkably similar, superimposing on backbone atoms with an rmsd of 0.7 A. Comparison of the two structures suggests that differences in solvent exposure of the heme and the electrostatic environment of the heme propionates, as well as in heme iron ligation, are the main determinants of midpoint potential in the two proteins. In addition, the crystal packing of both A. maxima cytochrome c-549 and cytochrome c(6) suggests that the proteins oligomerize. Finally, the cytochrome c-549 dimer we observe can be readily fit into the recently described model of cyanobacterial photosystem II.
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1F1F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arthrospira_maxima Arthrospira maxima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F1F OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f1f ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Structures of cytochrome c-549 and cytochrome c6 from the cyanobacterium Arthrospira maxima., Sawaya MR, Krogmann DW, Serag A, Ho KK, Yeates TO, Kerfeld CA, Biochemistry. 2001 Aug 7;40(31):9215-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11478889 11478889]
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</StructureSection>
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[[Category: Arthrospira maxima]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Limnospira maxima]]
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[[Category: Kerfeld, C A.]]
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[[Category: Kerfeld CA]]
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[[Category: Krogmann, D W.]]
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[[Category: Krogmann DW]]
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[[Category: Sawaya, M R.]]
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[[Category: Sawaya MR]]
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[[Category: Serag, A A.]]
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[[Category: Serag AA]]
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[[Category: Yeates, T O.]]
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[[Category: Yeates TO]]
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[[Category: cyanobacteria]]
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[[Category: cytochrome c6]]
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[[Category: heme]]
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[[Category: photosynthesis]]
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[[Category: protein structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:13:55 2008''
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Current revision

CRYSTAL STRUCTURE OF CYTOCHROME C6 FROM ARTHROSPIRA MAXIMA

PDB ID 1f1f

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