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2nu5

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==Crystal structure of a complex of griffithsin cocrystallized with N-acetylglucosamine==
==Crystal structure of a complex of griffithsin cocrystallized with N-acetylglucosamine==
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<StructureSection load='2nu5' size='340' side='right' caption='[[2nu5]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
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<StructureSection load='2nu5' size='340' side='right'caption='[[2nu5]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nu5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Grisq Grisq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NU5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nu5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Griffithsia_sp._Q66D336 Griffithsia sp. Q66D336]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NU5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.564&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gty|2gty]], [[2gux|2gux]], [[2gue|2gue]], [[2guc|2guc]], [[2gud|2gud]], [[2hyr|2hyr]], [[2nuo|2nuo]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu5 OCA], [https://pdbe.org/2nu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nu5 RCSB], [https://www.ebi.ac.uk/pdbsum/2nu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nu5 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nu5 OCA], [http://pdbe.org/2nu5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nu5 RCSB], [http://www.ebi.ac.uk/pdbsum/2nu5 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GRFIN_GRISQ GRFIN_GRISQ]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nu5_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/2nu5_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Grisq]]
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[[Category: Griffithsia sp. Q66D336]]
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[[Category: Wlodawer, A]]
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[[Category: Large Structures]]
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[[Category: Ziolkowska, N E]]
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[[Category: Wlodawer A]]
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[[Category: Antiviral protein]]
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[[Category: Ziolkowska NE]]
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[[Category: Domain swapping]]
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[[Category: Griffithsin]]
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[[Category: Hiv]]
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[[Category: Lectin]]
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[[Category: Mannose binding]]
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[[Category: Sar]]
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[[Category: Sugar binding protein]]
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Current revision

Crystal structure of a complex of griffithsin cocrystallized with N-acetylglucosamine

PDB ID 2nu5

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