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2w5v

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==STRUCTURE OF TAB5 ALKALINE PHOSPHATASE MUTANT HIS 135 ASP WITH MG BOUND IN THE M3 SITE.==
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<StructureSection load='2w5v' size='340' side='right' caption='[[2w5v]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
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==Structure of TAB5 alkaline phosphatase mutant His 135 Asp with Mg bound in the M3 site.==
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<StructureSection load='2w5v' size='340' side='right'caption='[[2w5v]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w5v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Antarctic_bacterium_tab5 Antarctic bacterium tab5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w5v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Antarctic_bacterium_tab5 Antarctic bacterium tab5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W5V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iuc|2iuc]], [[2w5w|2w5w]], [[2w5x|2w5x]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2iuc|2iuc]], [[2w5w|2w5w]], [[2w5x|2w5x]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkaline_phosphatase Alkaline phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.1 3.1.3.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alkaline_phosphatase Alkaline phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.1 3.1.3.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5v OCA], [http://pdbe.org/2w5v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w5v RCSB], [http://www.ebi.ac.uk/pdbsum/2w5v PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5v OCA], [https://pdbe.org/2w5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w5v RCSB], [https://www.ebi.ac.uk/pdbsum/2w5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5v ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5v_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5v_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Alkaline phosphatase|Alkaline phosphatase]]
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*[[Alkaline phosphatase 3D structures|Alkaline phosphatase 3D structures]]
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*[[User:Andrzej Lyskowski|User:Andrzej Lyskowski]]
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== References ==
== References ==
<references/>
<references/>
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[[Category: Alkaline phosphatase]]
[[Category: Alkaline phosphatase]]
[[Category: Antarctic bacterium tab5]]
[[Category: Antarctic bacterium tab5]]
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[[Category: Large Structures]]
[[Category: Bouriotis, V]]
[[Category: Bouriotis, V]]
[[Category: Feller, G]]
[[Category: Feller, G]]

Current revision

Structure of TAB5 alkaline phosphatase mutant His 135 Asp with Mg bound in the M3 site.

PDB ID 2w5v

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